Poster Presentation 29th Australian and New Zealand Bone and Mineral Society Annual Scientific Meeting 2019

Measures of physical performance as a predictor of fracture risk independent of BMD change: the Chungju Metabolic Disease Cohort study (#148)

Yejee Lim 1 , Jeonghoon Ha 2 , Ki Hyun Baek 2 , Moo-Il Kang 2
  1. Department of Internal Medicine , Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea
  2. Division of Endocrinology and Metabolism, Department of Internal Medicine , The Catholic University of Korea, Seoul, , Republic of Korea

Introduction

Measures of physical performance predict the risk of fractures, however, little data on the Korean population have been published. The aim of this study was to evaluate the association between physical performance and the risk of osteoporotic fracture (OF).

Methods

This study was performed in 4,015 adults 40 years or older living in the rural area of Chungju City. A second bone mineral density (BMD) examination was conducted approximately 4 years after a baseline examination. We used the one-leg standing time (OLST) and tandem stand for assessing static balance; timed up-and-go test (TUGT) for assessing dynamic balance; hand grip strength for assessing muscle power.

Results

Mean BMD was 0.664 ± 0.136 g/cm2, 0.802 ± 0.153 g/cm2, and 0.816 ± 0.179 g/cm2 for the femoral neck (FN), the total hip (TH), and the lumbar spine (LS), respectively. During the follow-up period, BMD of the FN and the TH decreased by 3.13 ± 6.41% and 2.87 ± 5.37%, respectively. In addition, mean percent change of BMD at the FN and the TH were associated with the incidence of OF regardless of the adjustment for confounders including age, BMI, and gender. However, BMD at the LS increased by 0.21 ± 9.42% during the follow-up period; the change of BMD at the LS was not associated with the incidence of OF (p = 0.120).

Grip strength, tandem stand, OLST, and TUGT were all associated with BMD at the FN (all p <0.001) and the incidence of OF (all p <0.001). However, only tandem stand (p <0.001) and OLST (p <0.001) were associated with the incidence of OF, even adjustment for age, BMI, gender, and the change of BMD at the FN.

Conclusions

Measurement of static balance including tandem stand and OLST could predict the risk of OF, independent of the change of BMD.